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[Nutritional importance of glutamine]

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In addition, cholesterol accumulation in MIM interferes with the assembly of respiratory supercomplexes, underlying the impairment in the respiratory capacity, stimulates the generation of superoxide anion resulting in oxidative stress, and stabilizes hypoxia inducible factor-1 (HIF-1), leading to metabolic reprogramming with impaired oxidative phosphorylation and stimulated glycolysis [136]

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The reliable pigment strategy is unglamorous and consists of three things