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Current treatment options are limited and often only slow disease progression

Several studies provide evidence for a close relationship between blood glutathione decrease and the pathogenesis of different inflammatory chronic diseases [22], [32]

FEBS Lett 487:361366

sloughing germinal epithelia of seminiferous tubules into the lumen with the absence of spermatogenic stages, exfoliation of germ cells with fewer & deformed spermatozoa (blue circle), vacuolations between germ cells (black arrow)