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These psychomotor effects of cannabis are mainly attributed to the 9 -tetrahydrocan-nabinol ( 9 -THC), the major psychoactive constituent in Cannabis sativa plant by acting on the cannabinoid (CB1) receptor that is highly expressed in the basal ganglia, the cerebral cortex and the cerebellum (Ameri, 1999

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A previous study revealed that Adlercreutzia and unclassified Erysipelotrichaceae in feces were positively associated with plasma PS levels, which indicated that these minor taxa may contribute to changes in PS levels [110]

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