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DOI: 10.1111/acel.14083 Circulation Research (2018) Ahajournals.org Reviewed the roles of SIRT1, SIRT3, SIRT4, SIRT6, SIRT7, and NAD+ across cardiovascular ageing, confirming protective roles against dyslipidaemia, obesity, type 2 diabetes, arrhythmia, cardiac fibrosis, hypertrophy, and ischaemia-reperfusion injury

Sensitivity for stroke diagnosis = 97%, specificity = 91%

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Upon TGF- attachment, ALK1 is induced to form a complex with ALK5, resulting in Smad1/5 activation (Finnson et al., 2008