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NQO1, NAD(P)H quinone oxidoreductase-1

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The substrate has been tested to possess great specificity even with addition of other soluble factors [glucose (GLU), glutathione (GSH), dopamine (DA), and uric acid (UA)] and ROS [TBHP, hypochlorite (OCl ), superoxide (O 2 ), NO, OH] in complete cell culture medium ( Cell Culture In order to compare the H 2 O 2 secretion from the single cells and cells in 3D spheroid formats, human hepatocellular carcinoma cells (HepG2, 60025, Bioresource Collection and Research Center, Hsinchu, Taiwan) are exploited in the experiments

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Crucial for achieving this goal is an improved understanding of the interactions between NPs and biological structures and tissues