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Les effets gastro-intestinaux les plus courants comprennent : des nauses passagres des douleurs abdominales ou des crampes des pisodes de diarrhe Ces effets sont souvent lis une intolrance aux agents de charge ou aux dulcorants prsents dans certains comprims croquer ou sublinguaux, comme le sorbitol ou le xylitol, plutt qu' la vitamine B12 elle-mme

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Patients with active cancer (any malignancy) must not use sermorelin, since increasing growth factors could potentially stimulate tumor growth

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Allergic reactions, some which can be potentially severe, have been reported during the use of viscosupplementation