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Supplementary Figure 1a-f ), which were enriched in multiple metabolic processes, among which amino acid metabolisms (e.g., glutamate metabolism, glycine and serine metabolism, and cysteine and methionine metabolism) being the most significantly downregulated pathways upon LDHB KD ( Figure 1b )

On the other hand, salt stress hypersensitivity is caused by the loss of function in the ethylene-positive regulators EIN2 and EIN3 (Nishiyama et al., 2011