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As mutated, it causes an early onset autosomal recessive PD

Chang Y, Zhai L, Peng J, Wu H, Bian Z, Xiao H

The researchers documented significantly lower frontal gray matter glutathione levels compared to healthy controls, directly linking this localized, severe oxidative stress to the clinical presentation of brain fog and memory loss

More importantly, multiple pro-inflammatory cytokines and chemokines were highly expressed by the BALF monocytemacrophages, suggesting that the cells are inflamed