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They enable precise manipulation of cellular signaling pathways, gene expression regulation, and enzymatic activity, all of which are essential for understanding disease mechanisms and molecular behavior

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Other than patients who have had their stomachs bypassed, there is also an autoimmune condition known as pernicious anemia that leads to a deficiency of intrinsic factor, lack of ability to absorb vitamin B12 and therefore poor availability of cobalamin (vitamin B12)

Improvement strategy for immune checkpoint blockade: a focus on the combination with immunogenic cell death inducers