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Messmer, M

Evaluated in controlled preclinical settings for synergistic extracellular matrix dynamics

7 Similarly, in the CASTOR clinical trial, patients with relapsed or refractory multiple myeloma who received the combination of daratumumab with bortezomib and dexamethasone had significantly prolonged PFS relative to those who received bortezomib and dexamethasone alone

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The NHS weight loss plan focuses on sustainable lifestyle modifications, including: Calorie reduction through portion control and healthier food choices Increased physical activity (minimum 150 minutes moderate-intensity exercise weekly, plus muscle-strengthening activities at least twice weekly) Behavioural strategies and goal-setting Referral to specialist weight management services based on local criteria Referral thresholds for weight management services vary by locality