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Because it is an autoimmune condition, Hashimotos can be associated with systemic symptoms such as fatigue, brain fog, joint discomfort, and other immune-related imbalances.

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Oxidative stress-induced DNA damage affects the coding region of mtDNA and influences oxidative phosphorylation, thereby altering the respiratory chain and unregulated production of ROS [11]

Kim, Taurine Directly Binds to Oligomeric Amyloid-beta and Recovers Cognitive Deficits in Alzheimer Model Mice, Advances in experimental medicine and biology 975 Pt 1 (2017) 233-241