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doi: 10.3390/ijerph16132255 20 SabriMASaber-AyadMM

Because Vitamin B12 and Folate are entirely co-dependent in this process, a deficiency or dysfunction in either one brings the entire methylation cycle to a grinding halt

In summary, exploring the function of PTMs on SSP will contribute to a deeper understanding of intracellular metabolic regulation under physiological and pathological conditions, providing foundations for innovative therapeutic strategies and diagnostic biomarkers