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Elevated NNMT slows the bodys ability to break down stored fat, making weight loss more difficult and contributing to conditions such as insulin resistance and poor metabolic health

However, its use is primarily for research purposes, and further studies are needed to fully understand its long-term effects and applications before it is approved by drug administration agencies or the FDA

When imputing missing data only, the underlying assumption is that body weight would be unaffected by discontinuation for trial participants lost to follow up

A lot of people now use B12 shots to lose weight as part of staying healthy