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N -alkylpyridinium reagents are very stable and undergo a 1,6-addition of thiols providing excellent chemoselectivity, regioselectivity and high modification efficiency even in the presence of other nucleophiles

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2 Mortality due to acetaminophen toxicity has been shown to be virtually eliminated when NAC is promptly administered

Supraspinal and spinal mediation of naloxone-induced morphine withdrawal in rats

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