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Irregular periods, hot flashes and night sweats, trouble sleeping, and vaginal issues are some of the most common perimenopause symptoms

Rebholz H, Friedman E, Castello J

In randomized, controlled human studies, GHKCu applied topically has been shown to increase collagen and elastin production in aged skin, improve dermal thickness and hydration, and significantly reduce wrinkle volume and depthcompared with controls supporting its role in skin rejuvenation and antiaging research

Alatzoglou KS, Turton JP, Kelberman D, Clayton PE, Mehta A, Buchanan C, Aylwin S, Crowne EC, Christesen HT, Hertel NT, Trainer PJ, Savage MO, Raza J, Banerjee K, Sinha SK, Ten S, Mushtaq T, Brauner R, Cheetham TD, Hindmarsh PC, Mullis PE, Dattani MT

Therefore, engineering for optimal engagement of the neonatal Fc receptor (FcRn) is crucial, as binding rescues IgG from intracellular degradation 14