Like other types of animal protein, collagen contains a type of amino acid called hydroxyproline ( Hydroxyproline is converted into oxalate in your body, which may increase levels of oxalate excretion in urine ( In one older study, consuming 30 grams of gelatin derived from collagen increased urinary oxalate excretion by 43% after 24 hours compared with a control group ( Several animal studies also show that consuming high amounts of hydroxyproline could increase oxalate levels in the urine, and therefore, may harm kidney health ( Other test-tube and animal studies suggest that these effects could be amplified in those with primary hyperoxaluria, a genetic disorder that affects oxalate metabolism and increases the risk of recurrent kidney stones ( However, keep in mind that most of these studies used concentrated amounts of hydroxyproline
Its ability to regulate inflammation and activate tissue remodeling pathways makes it valuable in dermatological and regenerative skin-focused programs
Consider rotating between formulas that feature different whole-food blends, perhaps one month focusing on berry-enriched formulas for anthocyanins, another month emphasizing green vegetable extracts for chlorophyll and phytonutrients
Limitations Substantial heterogeneity was observed between studies in brain and blood GSH in AD and MCI
10.1248/bpb.b20-00409 Biol
