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Impaired glucose metabolism Neurons primarily rely on glucose for energy production via oxidative phosphorylation (OXPHOS) in healthy brains

10.1007/s10803-014-2205-8 101 McCafferyP.DeutschC

Most disease-causing mutations in these proteins occur in low-complexity domains mediating liquid-liquid phase separation to alter protein conformation, which promotes the aggregation and disrupts RNA regulation while also generating additional toxicity

As you know, it has a part in Bolivia and another in Peru, as well as several inhabited islands that can be visited