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Description

Treatment of SAM was found to increase both global and CBS gene locus specific DNA methylation (Supplementary Fig

Lancet Infect

Control of sulfur partitioning between primary and secondary metabolism

(2) normal temperature plus exogenous GSH treatment (NT+GSH): added 0.25 mM GSH in nutrient solution one day before the treatments and maintained at 0.25 mM GSH in the nutrient solution during the treatment period

To investigate the function of CBS in this process, we silenced its expression by CRISPR/cas9 mediated gene knockout strategy (sg CBS ) in SCD erythroblasts (Fig