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In an incremental dose model using C57BL/6J male mice, a moderate APAP dose (300 mg/kg) induces robust liver regeneration at 24 hours, whereas a higher dose (600 mg/kg) results in severe liver injury accompanied by delayed regeneration, cell cycle arrest, and reduced Cyclin D1 expression (Bhushan et al

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The extra virgin olive oil phenolic oleacein is a dual substrate-inhibitor of catechol-O-methyltransferase

LHGJ20240243, LHGJ20230786), the Natural Science Foundation of Henan Province (No