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Common factors, such as smoking, medications, and metabolic conditions can also leave strong background signals 190,191 , and differences in how studies define behavioral or clinical phenotypes further reduce comparability

Orphan receptor NR4A3 is a novel target of p53 that contributes to apoptosis

Additionally, incorporating anti-inflammatory foods like turmeric, ginger, and omega-3-rich fish helps reduce gut inflammation and supports a balanced microbiome

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D-Serine, synthesized by serine racemase in both astrocytes and neurons, serves as a co-agonist at NMDA-type glutamate receptors, playing a pivotal role in modulating synaptic plasticity and possibly influencing neuronal recovery processes, although its role in axonal regeneration remains to be fully defined [101]