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Disorders of the RBC cytoskeleton lead to changes in overall shape of the cells such as spherocytosis and elliptocytosis

Although NR2B is essential for cognition processes within the adult, an overabundance may be hazardous due to the significant increase in Ca + conductance that could lead to excitotoxicity and neuronal death [21]

Furthermore, caution should be applied when narcotics, antihistamines or benzodiazepines are administered alongside clozapine, due to the risk of CNS depression