Users are essentially participating in uncontrolled self-experimentation, a reality that informed decision-making requires acknowledging
Step 3: Slowly rebuild routine (Week 3-6) Once baseline sensitivity is reduced, carefully reintroduce products: Week 3: Add hydrating serum (hyaluronic acid, ceramides, peptides other than copper) Week 4: Add niacinamide if desired (reduces inflammation, supports barrier) Week 5: Consider very gentle chemical exfoliant (mandelic acid once weekly) if skin is fully calm Week 6+: Only now consider reintroducing copper peptides if you still want to try them Rules for reintroduction: Add one product at a time Wait 5-7 days between new additions If anything causes reaction, stop and go back to previous step Take notes on what works and what doesn't Step 4: Reintroduce copper peptides properly (if desired) If you want to try copper peptides again after your skin has healed: Start differently this time: Use 0.5% concentration or lower Apply 2x per week only Start with small area (forearm test first, then small facial area) Wait 4 weeks before increasing frequency or concentration Pay attention to skin's response If problems recur: Copper peptides may not be right for your skin Consider alternatives (regular peptides without copper, retinoids, other collagen-boosting actives) Focus on barrier health and gentle anti-aging approaches Supplements and support for healing While healing damaged skin, these can help: Omega-3 fatty acids: 2-3g daily (reduces inflammation, supports skin barrier) Zinc: 30mg daily (healing, anti-inflammatory, supports skin health) Vitamin C: 1,000-2,000mg daily oral (collagen synthesis, healing) Collagen peptides: 10g daily (provides building blocks for skin repair) Don't supplement copper while healing from copper peptide damage
Gutman describes it as intimately involved in a glutathione-driven enzyme system that keeps vitamin C, vitamin E, and others in their reduced, active state
Data are presented as the mean SD of three or four biological replicates in three or four independent samples
(Malhi and Gores, 2008)
