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ATF4 activation upregulates GSH and dTTP pools in T315I-Bcr-Abl-32D cells Next, we want to address the questions of what causes the increases in dTTP and GSH biosynthesis in T315I-Bcr-Abl and whether blocking the upregulation of these two factors can increase JMF4073 sensitivity

In: Jacob-Lopes E, Queiroz MI, Maroneze MM, Zepka LQBT-H of F and F from M (eds) Handbook of Food and Feed from Microalgae: Production, Application, Regulation, and Sustainability

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This is possible because methionine is a precursor of S-adenosyl-methionine (AdoMet), which functions as a methyl group donor, a polyamine biosynthesis intermediate, and a precursor of ethylene [43]

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