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Removal of matriptase, a membrane-anchored serine protease that helps form TJs in the intestinal epithelial barrier, specifically in the intestinal epithelium, also leads to the development of colon adenocarcinoma [107, 108]

doi:10.1016/j.phrs.2021.105840

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To better understand your tap water, review your local annual water quality report or consider laboratory testing if you have a specific concern