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10.1136/svn-2018-000221 279 XuL.LiuY.ChenX.ZhongH.WangY

Placebo-controlled trial of oral laquinimod in multiple sclerosis: MRI evidence of an effect on brain tissue damage

To characterize the kinetic mechanism for Cn Acs1 inhibition by isoxazole 1 , we examined the dependence of Cn Acs1 inhibition by isoxazole 1 on the three substrates, as shown in Figs