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Antiobesity effect of Gynostemma pentaphyllum extract (actiponin): a randomized, double-blind, placebo-controlled trial

Compared to the DSS group, the TLYYH group showed significant alterations in 49 metabolites in positive ion mode (32 upregulated, 17 downregulated) and 60 metabolites in negative ion mode (23 upregulated, 37 downregulated

Expected results: Gradual improvement in skin tone uniformity within weeks of regular use

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TGF- stimulates Wnt secretion and activates the Wnt/-catenin signalling pathway through the TAK1 pathway to promote myofibroblast differentiation, which leads to myocardial fibrosis