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As mentioned above, MdDS mostly affects women (roughly 85% of the clinical population), with onset around the age of perimenopausal transition 9,10,8,5,11

In addition, it could accumulate in neutrophils to promote chemotaxis phagocytosis and with subsequent microbial killing

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Zinc is essential for the production of IFNs, especially IFN-, which plays a crucial role in antiviral immunity

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