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HPLC Analysis of an EHT Extract [00066] FIG

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Furthermore, several groups have reported that AR controls a spectrum of alternative splicing events that is independent of its traditional role in transcription of AR target genes, allowing AR to further finetune the CaP cell transcriptome [104, 105]

Taking into account all the above-mentioned, monitoring oxidative stress related-parameters during the course of CIPN could be helpful in clinical practice (Areti et al., 2014)

In conclusion, non-pharmacological therapies that focus on controlling the etiology of liver disease, improving nutrition, increasing muscle mass, mitigating triggers and risk factors, and enhancing coping mechanisms are significantly more effective in combating fatigue in cirrhosis compared to pharmacological treatments (Figure 2) (4, 9)