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Total cumulated nucleus-associated DAPI and PI fluorescence was assessed in a blinded fashion by apply an automated detection method (cellSens Dimension 1.18, Olympus, Count and Measure tool)

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A meta-analysis of seven studies including 1,757 participants with type 2 diabetes found that SGLT2 inhibitor therapy in combination with blood pressure medications (known as renin-angiotensin system blockers) was well-tolerated and resulted in greater improvement in blood pressure, glucose control, body weight, and indices of kidney function compared with the blood pressure drugs alone (Tian 2021)

For longer trips, consider a portable medication cooler that maintains 2 to 8 degrees Celsius

The performance metrics for the models on the test set, the fold changes and FDR values for the selected genes are shown in Fig 1 (A &B, and C respectively)