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All authors participated in the preparation of the manuscript and approved the final manuscript

Despite plentiful evidence showing improvement in acne, several studies have failed to show a significant reduction in sebum output after PDT with ALA.[67,68] However, one supportive study found that lower sebum excretion persisted even 20 weeks after multiple PDT sessions, but not after a single PDT session

Research on the design space of extraction process for Folium stevia formula granules based on consistency with standard decoction(in Chinese)

However, they do not yet provide robust longterm comparative outcome data (toxicity, quality of life [QoL], tumor control) sufficient to demonstrate a widened therapeutic window in this indication