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Acetylation of soluble TAU represents an early event in neurodegeneration, and blockade of CMA exacerbates the proliferation of pathogenic TAU in mice, worsening the disease state (178)

& Satija, R

Compared to M2-type macrophages, M1-type macrophages exhibit elevated expression of hepcidin antimicrobial peptide (Hamp), ferritin heavy chain (FTH), and ferritin light chain (FTL), with reduced levels of FPN and iron regulatory proteins 1/2 (IRP1/2), demonstrating enhanced iron storage capacity (96)

6q), possibly because of irreversible ROS-mediated modifications

plantarum activates toll-like receptors (TLRs) signaling, leading to the translocation of the pivotal structural protein Zonula occludens-1 (ZO-1) to the tight junction domain in intestinal models (165)