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These experiments demonstrate the feasibility of clinically translating p53-related oxidative stress pathways outside oncology [122]

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37 It was also found that inhibition of PI3K/Akt/mTOR signaling pathway can reverse TNF--mediated autophagy and cytokine secretion, thereby reducing the inflammatory response of RA, inhibiting RA-FLS cell proliferation, and promoting apoptosis

Metformin reduces thyrotropin levels in obese, diabetic women with primary hypothyroidism on thyroxine replacement therapy