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For an 80 kg test subject, this would give a weekly dosage range of between 2,400-4,800 g (2.4 4.8 mg)

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The above results show that GPX4 inhibitors, such as RSL3, are senolytic

Upon receptor binding, it initiates Gq-coupled intracellular signaling, thus activating phospholipase C, generating inositol trisphosphate, and mobilizing intracellular calcium

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