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Another study suggested that artesunate ameliorated LPS-mediated release of apoptotic proteins NLRP1, CASP-3, ASC, and CASP-1 in NR8383 cells by regulating SIRT1 expression in vivo (Liu Z

doi:10.1016/j.jnutbio.2010.10.005 Kansanen E, Kuosmanen SM, Leinonen H, Levonen AL (2013) The Keap1-Nrf2 pathway: mechanisms of activation and dysregulation in cancer