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The prasinezumab trial (PASADENA), however, showed significantly slower decline in MDS-UPDRS part III scores (a key secondary endpoint) at week 52 as well as consistent results in exploratory digital motor measures [207]

doi: 10.1530/eje.0.1480325

The relative change in current caused by hybridization () was calculated by dividing the difference between the peak currents before (I ss ) and after (I ds ) hybridization by the current before hybridization (I ss ) using equation (1): The relative current increase after hybridization with target diminished from 14.6% to 3.3% and 0.3% after hybridization with single base pair mismatch and noncomplementary sequences respectively

GLP-1 RAs produced greater BMI reductions than metformin in head-to-head comparisons

Almes M, Spraul A, Ruiz M, Girard M, Roquelaure B, Laborde N, Gottrand F, Turquet A, Lamireau T, Dabadie A, et al