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Secondly, sometimes the microbiota may not have antigens similar to the host structure, but it can induce co-stimulation and cytokine production through antigen presenting cells, leading to the activation of bystander T cells [72, 73]

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ME/CFS can affect multiple organs and is characterized by at least six months of moderate-to-severe symptoms affecting three core areas: Other common symptoms can include: These varied symptoms are a result of dysregulation across the neuro-immune system, hormonal regulation, and even cardiovascular and gastrointestinal systems

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