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No matter how polished or expensive those parts appear, the engine will not run better unless those pieces connect to actual working components of the engine

The overexpression of cathepsin B promoted the invasiveness and progression of breast cancer cells 116,117 , while downregulation of cathepsin B function by shRNA significantly reduced bone metastasis in mice breast cancer models 118

however, no significant effect was evident in the other treatment groups (Fig

Consistent with 30% weight loss at day 5, the glycerol concentrations were depleted in the sera of cysteine-deficient mice and were restored by cysteine-repletion-induced weight regain (Extended Data Fig

2002;71:223-30 pubmed Park B, Kang J, Lee S, Choi S, Shin Y, Ahn Y, et al