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More than 90% of patients in the Korean trial were on 3 daily doses of levodopa with a mean daily dose around 400 mg and average daily OFF-time of 3.4 h [126]

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36 However, oral naltrexone is not commonly prescribed for OUD because there is poor compliance and evidence suggests that it may not be more effective than placebo in treating OUD

Alpha tocopherols is the most active and is dominant in the body due to specific mechanisms that favor its accumulation, such as the liver binding alpha tocopherol to plasma lipoproteins

Domain-level covariance analysis for multilevel survey data with structured nonresponse