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In patients on dialysis the weekly dose of renal replacement therapy is an additional important factor

Hinson JA, Bucci TJ, Irwin LK, Michael SL, Mayeux PR (2002) Effect of inhibitors of nitric oxide synthase on acetaminophen-induced hepatotoxicity in mice

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10.1113/JP272613 J

These complexes demonstrated cytotoxicity comparable to cisplatin and oxaliplatin, and showed selective targeting for HER2-overexpressing NCI-N87 gastric cancer cells and BT-474 breast ductal carcinoma cells, both of which are resistant to apoptosis