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In conclusion, whatever medication that increases endogenous portal insulin (signaling) in T2DM patients, regardless of the glucose level (specifically sulfonylurea derivatives and peroxisome proliferatoractivated receptor [PPAR-] agonists, but not dipeptidyl peptidase-4 inhibitor [DPP4i], or glucagonlike peptide-1 [GLP-1] analogues) will lead to an increase in body weight, even when caloric intake is not increased

Linus Pauling Institute Oregon State University Reviewed in July 2024 by: Mary Ellen Sanders, Ph.D

Arwa Ibrahim Al-Mogherah, Mohamed Abbas Ibrahim,Maha Abdelzeem Hassan Saudi Pharmaceutical Journal 28 (2020) 1374-1382 Tarjani S Naik, Anubha Khale, Hema Kanekar International journal of Pharmaceutical and phytopharmacological Research 2249-6084 Muzammil Husain,Vinit V