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Likewise, in fish that received lipopolysaccharide (LPS) to stimulate inflammatory responses, the expression levels of mRNAs of anti-inflammatory cytokines in liver, intestine and kidney were up-regulated in fish fed HFD supplemented with betaine compared with fish fed HFD, while nf-kb and pro-inflammatory cytokines were down-regulated

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To address these challenges, liposome-based vaccine formulations tailored to specific administration routes have been developed to enhance bioavailability and improve the overall effectiveness of non-invasive vaccines (Aroffu et al