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Exposure of AIE adult rats to acute ethanol normalized the AIE-induced phenotypes to those of control rats: the heightened anxiety-like behaviors were attenuated, the decreased Lsd1+8a mRNA expression was normalized, and the increased H3K9me2 occupancy at the Bdnf exon IV promoter was normalized (40)

Concluding remarks The choice of an optimal model system depends on a balance between the main scientific question and the strengths and limitations of the particular model

462,463,464 CRS associated with CAR-T therapy Pathogenesis of CRS associated with CAR-T therapy CAR-T cell-associated CRS is a systemic condition characterized by the hyperactivation of immune effector cells and a diverse array of proinflammatory cytokines

10698962 52WheelerMD.ThurmanRG

Treatment with different concentrations of Fer-1 for 48 h resulted in increased cell viability across all Fer-1-treated groups, with the highest viability noted at 1 mol/l (Fig