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Borges G, Fong RY, Ensunsa JL, Kimball J, Medici V, Ottaviani JI, et al

For example, activation of the IRE1-XBP1 pathway produces XBP1s, which participates in the adaptive regulation of ERS and indirectly influences necroptosis by regulating the expression of certain anti-apoptotic proteins (Wang S

Consequently, it is imperative to explore the enzyme that mediates its endogenous generation, namely, lactyl-CoA synthase

Notably, mangiferin has been validated to trigger G2/M phase cell cycle arrest via regulation of the CDK1-cyclin B1 signaling pathway (4951)

4 The therapeutic targets and drugs of PCOS Given the multifactorial pathogenesis of PCOS, therapeutic strategies rarely involve a single intervention