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Kleniewska P, Pawliczak R

Study exclusion criteria may have selected patients at lower risk of overdose, and substantial loss to follow-up (approximately 80%) also may have biased estimates

Additional information Statement of Financial Support This study was enabled by funding from the Netherlands Organisation for Health Research and Development ZonMw (Grant number: 80-83600-98-10190)

10.1007/s00018-016-2207-0 89 KroemerG.GalassiC.ZitvogelL.GalluzziL

Users who began protocols in their forties or fifties and continued cycling for years describe maintaining physical and cognitive function that their peers have lost