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doi:10.20471/acc.2019.58.02.13

In general, cellular excitation is marked by cation fluxes across the plasma membrane

Notably, in the db/db- and the HG-treated SV40-MES-13 cells, the protective effect of astragaloside I on drug-induced renal fibrosis mediated by the Klotho/TGF-1/Smad2/3 pathway can be offset by the ITSA-1 (a HDAC3 agonist) (Zhang X

68 SchirchV.HopkinsS.VillarE.AngelaccioS

Protocols consisted of placebo supplementation during the first 6 weeks (glucose solution in 2 daily doses) and L-carnitine supplementation (two times a day, i.e., 2 g daily in water solution) after more 6 weeks