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All animal experiment protocols for this study were reviewed and approved by the Animal Ethics Committee of the Second Affiliated Hospital of Harbin Medical University (Approval No.: SYDW2021-076), and all procedures were conducted in accordance with the institutions animal care and use guidelines

Cysteine depletion induces pancreatic tumor ferroptosis in mice

Selank (N-Acetyl Selank) : Primarily used for its anti-anxiety and cognitive-enhancing effects without causing fatigue

Possible side effects include mild nausea, headache, injection site irritation, or water retention

Then StringTie ( was used to perform expression level for all mRNAs from input libraries by calculating FPKM (total exon fragments /mapped reads (millions) exon length (kB))