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doi: 10.1016/j.foodchem.2021.129357 40

Aspartame in rodents disrupts neurotransmission, exacerbates oxidative damage, and impairs learning through glutamatergic excitotoxicity and mitochondrial dysfunction [9]

Similarly, miRNA inhibitors are single-stranded RNAs that are complementary to endogenous miRNAs, which can reduce the effect of gene silencing by specifically inhibiting miRNA

While not dangerous, it can cause scars

Without supplementation, deficiency is nearly universal within 23 years People taking metformin long-term metformin use reduces B12 absorption by 1030% through calcium-dependent ileal uptake disruption [4] People taking PPIs or H2 blockers acid suppression impairs B12 release from food proteins