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Glutathione is essential because its the only antioxidant capable of working with enzymes

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Protein carbonyls and protein nitrotyrosine are widely used and chemically stable biomarkers of protein oxidation in SLE [92]

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PLoS ONE 7(10):e47442

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For example, levels of antioxidants including glutathione are significantly lower in mitochondrial and synaptosomal fractions of postmortem brains from Alzheimers disease patients when compared to age-matched controls (5)

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