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If you have not run your genetics, start there

In conclusion, ferroptosis is involved in the pathogenesis of DN, and targeting the inhibition of ferroptosis holds promise as a new pathway for treating DN

doi: 10.1152/japplphysiol.00744.2014

And its a form of programmed cell death (PCD) that occurs as a result of iron-dependent oxidative reactions different in both biochemistry and morphology from others (apoptosis, necrosis and autophagy) [26]