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doi: 10.3390/molecules27165099 31 DobroslaviE.GarofuliI

A key mechanism contributing to MDR involves the energy-dependent efflux of drugs from cancer cells, leading to decreased intracellular drug concentrations and reduced efficacy

Endogenous cysteine synthesis is predominantly achieved through the conversion of homocysteine (Hcy) and through GSH and protein degradation

Supplements to support treatment B12 is covered within the compound itself, but additional nutritional gaps commonly develop during tirzepatide therapy